RecruitingNCT07001982

Lumbar Spinal Stenosis and Central Sensitization

The Relationship Central Sensitization, Pain and Depression Patients With Lumbar Spinal Stenosis


Sponsor

Karabuk University

Enrollment

68 participants

Start Date

Jun 17, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

Lumbar spinal stenosis (LSS) functionally limits individuals by causing pain in both the waist and the legs during activity and walking. Pain is, therefore, an important problem for patients. Pain lasts for years in LSS and thus becomes chronically persistent. As a result, persistent pain can cause sensitization due to a decrease in the pain threshold. This condition affects patients not only biomedically but also biopsychosocially. For this reason, various sleep disorders and mood disorders can develop in patients. Therefore, this study aimed to examine the relationship between central sensitization and pain, disability, sleep and depression in patients with LSS.


Eligibility

Min Age: 45 YearsMax Age: 80 Years

Plain Language Summary

Simplified for easier understanding

This study is investigating "central sensitization" — a condition where the nervous system becomes extra sensitive to pain signals — in people with lumbar spinal stenosis, a narrowing of the spinal canal in the lower back that causes pain and walking difficulty. **You may be eligible if...** - You are between 45 and 80 years old - You have been diagnosed with lumbar spinal stenosis confirmed by MRI - You have had lower back or leg pain lasting at least 3 months - You are willing to participate **You may NOT be eligible if...** - You have a serious neurological disease (e.g., Parkinson's, MS, stroke/hemiplegia) - You had lumbar spine surgery in the past year - You have cancer affecting the spine or active cancer elsewhere - You have significant joint disease in your legs or prior lower limb surgery - You have a psychological disorder or peripheral vascular disease - You are unable to cooperate with the study procedures Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(1)

Karabuk University

Karabük, Turkey (Türkiye)

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NCT07001982


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