RecruitingNot ApplicableNCT07002892

Effectiveness of Corticosteroid and 5% Dextrose Versus USG-guided Ozone Injections in Patients With Carpal Tunnel Syndrome: Three Blind Randomized Studies


Sponsor

Yunus Burak Bayır

Enrollment

72 participants

Start Date

Jan 1, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

Effectiveness of corticosteroid and 5% dextrose versus USG-guided ozone injections in patients with carpal tunnel syndrome: Three blind randomized studies


Eligibility

Min Age: 18 YearsMax Age: 65 Years

Inclusion Criteria5

  • Being between 18-65 years old
  • Have been clinically diagnosed with carpal tunnel syndrome
  • Confirmation of moderate CTS diagnosis with EMG
  • Having typical CTS symptoms for at least 3 months
  • Not having benefited from splinting and rest

Exclusion Criteria4

  • History of polyneuropathy, brachial plexopathy, thoracic outlet syndrome or wrist surgery
  • History of inflammatory arthritis, hypothyroidism, pregnancy, rheumatologic disorders or pacemaker
  • Current warfarin use, previous corticosteroid injection for CTS, trauma or neoplasm at the injection site, hypersensitivity to corticosteroids or skin infection(injection site)
  • G6PD deficiency, hyperthyroidism, thrombocytopenia, severe cardiovascular instability and those receiving ACE inhibitors

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Interventions

DRUGOzon treatment

Each patient will receive 2 ml 10 μg/ml ozon perineural injection into the median nerve under US guidance, for 1 session.

DRUGSteroid treatment

Each patient will receive 2 ml:(1 ml betamethasone dipropionate+1ml saline) perineural injection into the median nerve under US guidance, for 1 session.

DRUGDextrose 5%

Each patient will receive 2 ml %5 dextrose perineural injection into the median nerve under US guidance, for 1 session.


Locations(1)

Ankara Etlik City Hospital

Ankara, Turkey (Türkiye)

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NCT07002892