RecruitingPhase 4NCT07004192

The Role of hCG in Thawed Embryo Transfer


Sponsor

Fertility Center of Las Vegas

Enrollment

220 participants

Start Date

Jun 2, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

This prospective randomized trial will assess the relevance, if any, of a corpus luteum induced by hCG in transfers of thawed embryos.


Eligibility

Sex: FEMALEMin Age: 18 Years

Inclusion Criteria5

  • Female adult expecting to receive transfer of a thawed embryo.
  • At least one available frozen blastocyst of transferrable quality.
  • Non-menopausal female with at least one antral follicle.
  • Use of pre-implantation genetic testing (PGT), embryos derived from donor oocytes and/or donor sperm, a gestational carrier, and history of prior transfer(s) regardless of outcome are allowed.
  • Subsequent embryo transfers after failed transfers under this study are allowed, but not after a transfer that has resulted in ongoing pregnancy at ten weeks gestation under this study.

Exclusion Criteria7

  • Minors (age<18 years).
  • Use of embryo(s) frozen at another center.
  • Patient insistent on transfer of two embryos.
  • Patient or partner unable to provide informed consent in English.
  • Patient already enrolled in any other research study for her embryo transfer.
  • History of anti-phospholipid syndrome or any other indication for use of Lovenox in pregnancy.
  • Patient for whom the physician assesses this protocol is inappropriate or unsafe.

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Interventions

DRUGHCG injection

5000 IU hCG injection

OTHERNo intervention

No hCG administered in this group.


Locations(1)

Fertility Center of Las Vegas

Las Vegas, Nevada, United States

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NCT07004192


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