RecruitingNot ApplicableNCT07006142

Effect of Prolonged Fasting Time on Gastric Residual Volume in Patients Taking GLP1 Receptor Agonists


Sponsor

Mayo Clinic

Enrollment

150 participants

Start Date

Aug 1, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

The aim of this study is to determine whether a modified fasting protocol can reduce the potential risk of aspiration for patients currently prescribed GLP1-RAs.


Eligibility

Min Age: 18 Years

Inclusion Criteria1

  • Patients undergoing elective upper endoscopy with gastroenterology team

Exclusion Criteria9

  • Urgent or emergent procedure
  • Inclusion of colonoscopy or antegrade small bowel enteroscopy in planned procedure
  • Upper GI barium study performed in past 24 hours.
  • Gastroparesis
  • Achalasia
  • Pancreatitis
  • Use of outpatient pro-motility medications
  • Patient refusal
  • Inability for patient to provide own consent

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Interventions

OTHERModified Fasting Guidelines

Patients will follow a full-liquid diet 48 hours prior to their procedure, clear liquid diet 24 hours prior to their procedure, and nothing by mouth (NPO) after midnight on the day of their procedure


Locations(1)

Mayo Clinic in Rochester

Rochester, Minnesota, United States

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NCT07006142


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