RecruitingEarly Phase 1NCT07012486

Efficacy of Dihydroartemisinin for Treating Female Androgenetic Alopecia

A Pilot Study to Evaluate the Therapeutic Effect of Dihydroartemisinin on Female Androgenetic Alopecia


Sponsor

Shanghai Zhongshan Hospital

Enrollment

30 participants

Start Date

Jun 1, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

The goal of this clinical trial is to learn if dihydroartemisinin (DHA) works to treat Androgenetic Alopecia (AGA) in female adults. The main question it aims to answer is: • Does DHA increase terminal hair follicles in the vertex area. Researchers will compare oral DHA plus topical minoxidil to topical minoxidil alone in female patients with AGA to see if DHA works to alleviate AGA. Participants will: * Receive oral DHA every day plus topical minoxidil or use topical minoxidil alone for 6 months. * Visit the clinic once every month for checkups and tests.


Eligibility

Sex: FEMALEMin Age: 18 YearsMax Age: 40 Years

Inclusion Criteria2

  • Clinically diagnosed with androgenetic alopecia (AGA)
  • No pregnancy plans within the next 6 months

Exclusion Criteria4

  • Patients who received systemic medications for hair loss within the past 2 months
  • Use of topical medication for hair loss within the past 2 weeks
  • Pregnancy or lactation
  • Patients with known severe diseases of vital organs (e.g., heart, liver, kidney) or malignancies.

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Interventions

DRUGOral DHA + Topical minoxidil 5%

DHA 20mg tid po plus daily topical minoxidil 5% for 180 days

DRUGTopical Minoxidil 5%

Topical minoxidil 5% daily for 180 days


Locations(1)

Zhongshan Hospital Fudan University

Shanghai, Shanghai Municipality, China

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NCT07012486


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