RecruitingEarly Phase 1NCT07016555

Burning Mouth Syndrome: Symptoms and Management


Sponsor

University of Massachusetts, Amherst

Enrollment

50 participants

Start Date

Jun 11, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

This research study aims to evaluate how an oral cooling spray, currently a commercial dietary supplement, impacts symptoms associated with burning mouth syndrome (BMS). This study will examine symptoms, frequency, and severity, along with other related side effects of BMS on food intake, enjoyment, and quality of life.


Eligibility

Min Age: 18 Years

Inclusion Criteria9

  • Have buring mouth syndrome or experience oral burn
  • Live in the United States
  • At least 18 years old
  • Having been diagnosed or suspected diagnosis of burning mouth syndrome or suffer from chronic oral burn without any identifiable causative lesion
  • No tongue or cheek piercings
  • No history of cancer
  • No recent or scheduled dental treatment
  • No history of gum disease
  • No aversions to mint or hop extracts

Exclusion Criteria2

  • Have recently undergone dental treatment in the last three months or have plans to undergo dental treatment (e.g., fillings, crowns, root canals, extractions, or other dental procedures) in the coming month.
  • Have started any new treatments for BMS in the last 3 months or have plans to start new treatments in the coming month.

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Interventions

DIETARY_SUPPLEMENTOral cooling spray

Use oral spray 3 times per day for 2 weeks


Locations(1)

UMass Amherst

Amherst, Massachusetts, United States

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NCT07016555


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