Effects of Dietary Nitrate in Women With Secondary Amenorrhea

This study is exploring whether drinking beetroot juice — which is rich in dietary nitrate — can improve muscle performance and exercise recovery in young women who have stopped having periods (secondary amenorrhea) due to excessive exercise, disordered eating, or stress. The lack of estrogen associated with secondary amenorrhea may reduce a molecule called nitric oxide, which affects muscle and blood vessel function, and researchers believe nitrate in beetroot juice could compensate for this. Women aged 18 to 44 who have missed more than 3 consecutive periods (if previously regular) or more than 6 (if previously irregular) are eligible, excluding those with conditions like PCOS, thyroid disease, current hormonal contraceptive use, or eating disorders. Participants will consume either nitrate-rich or nitrate-depleted beetroot juice and undergo exercise and muscle function tests at the study site. This summary was prepared to help patients understand the study in plain language.