Induction of Migraine Attacks With Aura Using Calcitonin Gene-Related Peptide
Induction of Migraine Attacks With Aura Using Calcitonin Gene-Related Peptide: A Randomized Clinical Trial
Danish Headache Center
21 participants
Jun 27, 2025
INTERVENTIONAL
Conditions
Summary
Calcitonin gene-related peptide (CGRP) is a key neuropeptide in migraine pathophysiology and treatment. This study investigates whether CGRP administration can trigger aura in individuals with a diagnosis of migraine with aura.
Eligibility
Plain Language Summary
Simplified for easier understanding
This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.
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Interventions
The participants will receive a continuous intravenous infusion of 1.5 μg/min of CGRP over 60 minutes.
The participants will receive a continuous intravenous infusion of 60 mL of placebo (isotonic saline) over 60 minutes.
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT07021859