RecruitingNot ApplicableNCT07023952

Effect of Phenol Addition to Laser Treatment on Epithelialization and Healing Process in Pilonidal Sinus

Effect of Phenol Addition to Laser Treatment on Epithelialization and Healing Process in Pilonidal Sinus: A Prospective Randomized Controlled Clinical Trial


Sponsor

Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital

Enrollment

130 participants

Start Date

May 1, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

This study compares two treatment approaches for pilonidal sinus disease: laser treatment alone versus laser treatment combined with phenol application. Pilonidal sinus is a common condition that affects young adults and can cause significant discomfort and time off work. Participants will be randomly assigned to receive either laser treatment only (Group A) or laser treatment plus phenol application (Group B). Both treatments are minimally invasive and performed under local anesthesia as day surgery procedures. The main goal is to determine if adding phenol to laser treatment speeds up the healing process (epithelialization) and improves patient outcomes. We will measure healing time, pain levels, return to daily activities, and quality of life over a 3-month follow-up period. This research may help develop more effective treatment protocols that reduce healing time and improve patient comfort for people with pilonidal sinus disease.


Eligibility

Min Age: 18 Years

Inclusion Criteria5

  • Age 18 years and older
  • Primary pilonidal sinus disease
  • Three or fewer pit counts
  • Willing to participate in the study and signed informed consent form
  • Able to attend follow-up visits

Exclusion Criteria9

  • Age under 18 years
  • More than three pit counts
  • Acute abscess presentation
  • Bilateral lateral extension
  • Recurrent pilonidal sinus disease
  • Immunocompromised patients
  • Patients unable to attend follow-up visits
  • Pregnancy (if applicable)
  • Severe comorbidities that contraindicate surgery under local anesthesia

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Interventions

PROCEDURELaser Treatment

Minimally invasive laser ablation procedure performed under local anesthesia for pilonidal sinus treatment. Laser energy is delivered through a fiber optic probe inserted into the sinus tract to achieve thermal ablation of the sinus cavity.

DRUGCrystallized Phenol

rystallized phenol is applied directly into the pilonidal sinus channels after cleaning and curettage. The phenol remains in contact for a specified duration before being neutralized with normal saline irrigation.


Locations(1)

Sancaktepe Sehit Prof. Dr. Ilhan Varank Training and Research Hospital

Istanbul, Other, Turkey (Türkiye)

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NCT07023952


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