A Phase 3 Study of HRS-8080 Versus Treatment Chosen by Physicians in Locally Advanced and Metastatic Breast Cancer

This Phase 3 study is testing a new hormone therapy drug called HRS-8080 compared to treatments chosen by the physician in women with locally advanced or metastatic breast cancer that is hormone receptor-positive. **You may be eligible if...** - You are a woman between 18 and 75 years old - You have locally advanced or metastatic breast cancer confirmed by biopsy - You have already received 1 to 2 lines of hormonal therapy - You are in good physical condition (ECOG 0–1) - Your life expectancy is greater than 6 months - Your organ function (blood, liver, kidneys) is adequate **You may NOT be eligible if...** - Your disease is progressing so quickly that hormone therapy is not appropriate - You have serious heart disease - You have uncontrolled cancer-related pain - You have an active serious infection or active hepatitis - You have significant uterine lining abnormalities - You are pregnant or breastfeeding Talk to your doctor to see if this trial is right for you.