RecruitingNCT07024680

Real World Study of Effectiveness of Sunitinib or Sorafenib to Chinese Unresectable Locally Advanced or Metastatic PRCC

Real World Study of Effectiveness of Sunitinib or Sorafenib as First Line Therapy to Chinese Unresectable Locally Advanced or Metastatic Papillary Renal Cell Carcinoma: a Multi-center, Retrospective, Observational Study


Sponsor

AstraZeneca

Enrollment

150 participants

Start Date

Mar 31, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

This is a multi-center, observational, retrospective study designed to characterize the effectiveness and safety of sunitinib or sorafenib monotherapy in the treatment of Chinese adult patients with unresectable and locally advanced or metastatic PRCC, who have not received any prior systemic anticancer therapy in the metastatic setting. Electronic medical record (EMR) data of patients with 1L sunitinib or sorafenib monotherapy will be screened from Grade-A Tertiary hospitals in China. The study period is from 1st September 2007 to 31st December 2024.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This is a real-world observational study looking at how well the drugs sunitinib or sorafenib work in Chinese patients with advanced or metastatic papillary renal cell carcinoma (a specific type of kidney cancer) when used as the first treatment. **You may be eligible if...** - You are 18 or older - You have been diagnosed with unresectable locally advanced or metastatic papillary renal cell carcinoma (PRCC) - You received sunitinib or sorafenib as your first-line treatment - You have a tumor assessment or clinical visit on record within 6 months of starting treatment **You may NOT be eligible if...** - You have papillary urothelial carcinoma (a different type of kidney cancer) - You had a separate cancer diagnosis in the past 5 years - You received another systemic cancer treatment for PRCC before sunitinib or sorafenib (exceptions apply) Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERObservational, None intervention

Observational, None intervention


Locations(1)

Fudan University Shanghai Cancer Center

Shanghai, Shanghai Municipality, China

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NCT07024680


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