Physician Response Evaluation With Contextual Insights vs. Standard Engines - Artificial Intelligence RAG vs LLM Clinical Decision Support
Comparing Clinical Key AI and GPT-4 for Diagnostic Reasoning and Management Decisions
Montefiore Medical Center
26 participants
Jul 3, 2025
INTERVENTIONAL
Conditions
Summary
Clinical decision support tools powered by artificial intelligence are being rapidly integrated into medical practice. Two leading systems currently available to clinicians are OpenEvidence, which uses retrieval-augmented generation to access medical literature, and GPT-4, a large language model. While both tools show promise, their relative effectiveness in supporting clinical decision-making has not been directly compared. This study aims to evaluate how these tools influence diagnostic reasoning and management decisions among internal medicine physicians.
Eligibility
Inclusion Criteria2
- Internal medicine residents
- Internal medicine attending physicians
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Interventions
Medical information platform which uses retrieval-augmented generation to access medical literature
A chatbot application developed that uses GPT-4, a large language model, to engage in conversational interactions with users.
Locations(2)
View Full Details on ClinicalTrials.gov
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NCT07037940