RecruitingNCT07040332

Pathogenesis and Inflammatory Phenotype of Allergic Bronchopulmonary Aspergillosis


Sponsor

Qianfoshan Hospital

Enrollment

140 participants

Start Date

May 10, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

This study aims to reveal the immune and inflammatory regulatory molecular mechanisms related to the progression of allergic bronchopulmonary aspergillosis (ABPA), and to build a precision typing based on inflammation and identify the biomarkers of typing, and to explore the clinical outcomes of different inflammatory phenotypes.


Eligibility

Min Age: 18 Years

Inclusion Criteria2

  • Meets the diagnostic criteria for allergic bronchopulmonary aspergillosis.
  • Meets the diagnostic criteria for fungal-sensitized asthma.

Exclusion Criteria8

  • Human immunodeficiency virus infection.
  • Malignant tumor.
  • Blood system disease.
  • autoimmune system disease.
  • History of pulmonary tuberculosis.
  • Patients with a history of smoking or still smoking.
  • Invasive pulmonary fungal disease.
  • Contraindications electronic bronchoscopy

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Interventions

OTHER

No intervention


Locations(1)

Department of Respiratory, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, #16766, Jingshi Road, Jinan City, Shandong Province, China

Jinan, Shandong, China

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NCT07040332


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