RecruitingNot ApplicableNCT07040904

Mindfulness to Enhance Cognitive Health in Latinx Older Adults

Sponsor

Washington University School of Medicine

Enrollment

60 participants

Start Date

Dec 10, 2024

Study Type

INTERVENTIONAL

Conditions

Mindfulness Alzheimer's Disease Related Dementia

Summary

The primary objective of the proposed research is to investigate the promise and underlying mechanisms of mindfulness training as a preventative lifestyle intervention to enhance cognitive health in Latinx older adults, thereby mitigating risk of Alzheimer's Disease (AD) in a population that may be particularly vulnerable.

Eligibility

Min Age: 65 Years

Inclusion Criteria6

Hispanic/Latinx
Age 65 and older
Male, female, or non-binary
Community living
Medically stable and willing to undergo the study procedures
No extensive mindfulness training experience

Exclusion Criteria5

Clinically unstable psychiatric disorder that requires immediate treatment (e.g., ECT)
Medical conditions suggesting significantly shortened lifespan (e.g., metastatic cancer) or prohibiting safe participation in the interventions/assessments (e.g., Parkinson's disease, musculoskeletal conditions)
Sensory impairment (hearing, vision) preventing participation
Current alcohol or substance abuse
Current/concurrent cognitive training known to affect neuroplasticity (e.g., brain-training programs), or other interventions expected to affect neuroplasticity significantly (e.g., psychedelics, cholinesterase inhibitors, high-dose sedatives).

Interventions

BEHAVIORALmindfulness

MBSR: Mindfulness Program A novel and culturally-adapted version of the well-validated mindfulness-based stress reduction (MBSR) course will be used for the intervention. The adapted program curriculum embeds core MBSR principles and practices within a culturally responsive didactic framework developed directly from community focus-group feedback. The course will be delivered via a group meeting across 8 weeks, with weekly classes held at a local community center. All classes will be held in hybrid format, with most participants attending in person, but with a live-stream option offered via Zoom.