Molecular and Cellular Profiling of Uterine Lavage Collected During Gynecologic Surgery

This study is collecting fluid samples from inside the uterus during gynecologic surgery to study the molecular and cellular makeup of the uterine environment. The goal is to better understand the biology of the uterus and fallopian tubes, which may eventually help in detecting gynecologic cancers earlier or understanding how they develop. **You may be eligible if...** - You are 18 or older - You are scheduled for gynecologic surgery at Stanford Healthcare - You have an intact uterus and cervix - You have at least one intact fallopian tube and ovary (on the same side) - You are willing and able to provide written informed consent **You may NOT be eligible if...** - You have a known diagnosis of endometrial or cervical cancer, or precancerous changes in those areas - You have had both fallopian tubes removed or had a tubal ligation - You have an IUD in place - You have active uterine bleeding at the time of surgery - You have a positive pregnancy test - You are unable to provide informed consent Talk to your doctor to see if this trial is right for you.