RecruitingPhase 4NCT07044726

Betadine vs Sterile Water for Periurethral Preparation

Betadine vs Sterile Water for Periurethral Preparation Prior to Straight Catherization in the Clinic Setting: A Randomized Controlled Trial


Sponsor

University of Louisville

Enrollment

148 participants

Start Date

Jun 30, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

The purpose of this study is to determine whether cleaning of the urethra, or external opening to the bladder, with sterile water (water that has been treated to remove bacteria and living organisms) vs Betadine also known as Povidone-Iodine (a medical grade cleaning solution) changes the rates of bacteria in the urine after a temporary catheter, or draining tube, is placed into the bladder. Chemical antiseptics, including Betadine, are the current standard of care. An additional goal of this study is to determine whether cleaning of the urethra, or external opening to the bladder, with sterile water vs betadine changes the amount of discomfort or pain patients experience with placement of a temporary catheter, or draining tube, in the bladder.


Eligibility

Sex: FEMALEMin Age: 18 Years

Inclusion Criteria2

  • Aged 18+
  • Patient undergoing in office straight catherization

Exclusion Criteria7

  • History of culture proven recurrent urinary tract infection (2 in any 6-month period or 3 in any 12-month period)
  • Urine Analysis with +Nitrites
  • Catherization for any reason in the last 4 weeks
  • History of Iodine allergy
  • Patients unable to speak English
  • Patient does not have the capacity to consent
  • -3rd trimester pregnancy

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Interventions

DRUGPovidone-Iodine

Providone-Iodine for periurethral preparation

DRUGSterile water

Sterile water for periurethral preparation


Locations(2)

UofL Physicians - Urogynecology Springs Urogynecology Office

Louisville, Kentucky, United States

UofL Health - Urogynecology Mary & Elizabeth Hospital, Medical Plaza 3

Louisville, Kentucky, United States

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NCT07044726


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