VIM+PTT MRgFUS for PD

This study is testing a focused ultrasound brain procedure for Parkinson's disease that targets two areas simultaneously — the VIM (a movement-control area) and another pathway (PTT). The procedure uses MRI-guided focused ultrasound waves to create a tiny, precise area of treatment in the brain without surgery, aiming to reduce tremor and other Parkinson's symptoms. **You may be eligible if...** - You have a diagnosis of Parkinson's disease - You have significant tremor or motor symptoms not well controlled by medication - You are a candidate for focused ultrasound based on brain imaging - You are able to undergo MRI **You may NOT be eligible if...** - You have metal implants in your head that are incompatible with MRI - You have had prior brain surgery or deep brain stimulation - You have significant cognitive impairment or other neurological conditions - You have uncontrolled medical conditions - You are pregnant Talk to your doctor to see if this trial is right for you.