RecruitingNot ApplicableNCT07045064

Aerobic Versus Resistive Intradialytic Training Effect on Atherogeinc Index in Hemodialysis Patients


Sponsor

Cairo University

Enrollment

60 participants

Start Date

Jul 4, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

the goal of the clinical trial is to study the effect of aerobic and resistive exercises on atherogenic index in hemodialysis patients the study will include three groups of both sex the first group will participate in aerobic exercise ,the second group will participate in resistive exercise and the third group will be control group


Eligibility

Min Age: 40 YearsMax Age: 60 Years

Plain Language Summary

Simplified for easier understanding

This study is comparing two types of exercise — aerobic (like cycling) versus resistance training (like weightlifting) — done during dialysis sessions, to see which better reduces cardiovascular risk in patients on hemodialysis (kidney dialysis). It measures a specific blood marker called the atherogenic index, which reflects heart disease risk. **You may be eligible if...** - You are on regular hemodialysis for kidney failure - You are medically stable and able to do light-to-moderate exercise - You are willing to exercise during your dialysis sessions **You may NOT be eligible if...** - You have serious heart or lung conditions that make exercise unsafe - You have physical limitations that prevent you from exercising - You are unable or unwilling to participate in the exercise program Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERAerobic exercise without medication

twenty patients will participate in moderate intensity intradialytic aerobic training for 12 weeks. (3 times per week). Using Horizontal electromagnetically braked cycle ergometer during the first half of the dialysis session. (1) Frequency: received intradialytic, lower-limb, cycling exercise three times per week on alternative days (2) Intensity: the intensity of exercise will be at 12-14 (moderate-intensity: somewhat hard or reports of feeling a little bit tired but still ok to continue) based on the Borg's Perceived Exertion Rating Scale Appendix III (a rating of 6 perceiving "no exertion at all" to 20 perceiving a "maximal exertion" of effort) ,Appropriate speed and grade of resistance were adjusted to achieve the required intensity. (3) Time: the duration of each exercise session consisted of a 5-min warm-up in form of circulatory exercise.

OTHERresistive exercise without medication

Twenty patients will participate in moderate intensity intradialytic resistive training for 12 weeks. (3 sessions per week) using ankle weights. During session: The warming up phase for 5-minute in form of circulatory exercises, then the main exercise phase and then cooling down phase for 5 minutes. in form of circulatory exercises. The training protocol consisted of five lower-body resistance exercises using ankle weights 3 days/week, The intensity of the program will be moderate, starting with two sets of each exercise at 60% of each patient's three repetition max (3-RM) strength, progressing to three sets per session, with additional weight added as tolerated

OTHERcirculatory exercise without medication

this group will include 20 patients will participate in circulatory exercises and will be evaluated at the beginning and at the end of the study.


Locations(2)

National Institute of Kidney and Urology, Mataria

Cairo, Select State, Egypt

National Institute of Kidney and Urology, Mataria

Cairo, Egypt

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NCT07045064


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