Methoxyflurane for IUD Insertion and Endometrial Biopsy

This study is testing whether inhaling Methoxyflurane (a fast-acting pain reliever available through a handheld Penthrox inhaler) reduces pain during IUD insertion or endometrial biopsy compared to a placebo inhaler. These are common gynecological procedures that can be uncomfortable, and the study is looking for better non-opioid options for pain relief. You may be eligible if you are 18 to 65 years old, scheduled for an IUD insertion (first-time insertions only) or endometrial biopsy, speak English, and do not have chronic pain conditions, liver or kidney disease, or an allergy to methoxyflurane. Participation involves inhaling the assigned medication just before your procedure and rating your pain level 5 minutes afterward. This summary was prepared using AI to help patients understand this research.