RecruitingNot ApplicableNCT07047430

The Airports, Air Quality, and Asthma (AAA) Study


Sponsor

University of Washington

Enrollment

60 participants

Start Date

Jun 1, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

For children with asthma, exposure to indoor air pollution increases the risk of a serious asthma exacerbation, which can be life-threatening. Interventions aimed at improving indoor air quality, including use of a portable air cleaner with a high-efficiency particulate air (HEPA) filter, can reduce this risk, but the effectiveness, feasibility and acceptability of HEPA air cleaners varies by setting. In collaboration with a community health worker (CHW) delivered asthma education program, the investigators are conducting a randomized clinical trial to evaluate the effectiveness of HEPA air cleaners to improve indoor air quality and child asthma health in South King County of Washington state, a vulnerable community impacted by air pollution from airports and highway traffic. Key features of the Airports, Air Quality and Asthma (AAA) design include integration of CHWs into study procedures, including CHWs recruited from community-based organizations, into multiple aspects of the trial protocol. The investigators aim to recruit up to N=60 children with asthma randomized into intervention and control groups in a 1:1 ratio, conduct baseline assessments of indoor air quality and airway health, and collect repeated assessments of air quality and airway health during the three-month intervention period and after the trial concludes. Study findings will inform future approaches to integrate HEPA air cleaners into existing CHW asthma education programs in this and similar communities.


Eligibility

Min Age: 6 YearsMax Age: 12 Years

Plain Language Summary

Simplified for easier understanding

This study is looking at whether air pollution from Seattle-Tacoma International Airport worsens asthma symptoms in children who live nearby. Researchers will track air quality and asthma flare-ups in children living within 10 miles of the airport to understand the relationship between aircraft emissions and childhood asthma. **You may be eligible if...** - Your child is 6–12 years old with a doctor-diagnosed asthma - Your child lives within 10 miles of Seattle-Tacoma International Airport (based on zip code) - Your child lives with you at least 5 nights per week with no plans to move in 3 months - You are comfortable participating in the study in English **You may NOT be eligible if...** - Your child has severe asthma (daily symptoms every day for the past 14 days, or 2+ hospitalizations for asthma in the past year) - Multiple members of the same household have asthma and are eligible for the county asthma program Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

DEVICEPortable air cleaner with HEPA filter

The Winix 9800 is a true HEPA air cleaner that has been AHAM (Association of Home Appliance Manufacturers) Verifide® for rooms that are 500 square feet in size. The air cleaner has a washable fine mesh pre-filter that captures large airborne particles, an activated carbon filter that reduces volatile organic compounds and odors, and a true HEPA filter that captures 99.99% of airborne allergens as small as 0.003 microns in size.

DEVICELess effective portable air cleaner (no HEPA)

Winix 9800 air cleaner, with data logging energy use monitor is installed in the child's bedroom. In the sham group, the Winix 9800 true HEPA filter and activated carbon filter were removed. This was an internal modification and not visible to the user. The air cleaner still included a washable fine mesh pre-filter that captures large airborne particles.


Locations(1)

University of Washington

Seattle, Washington, United States

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT07047430


Related Trials