Clinicopathological Value of p16 Expression in Colorectal Carcinoma
Clinicopathological Value of p16 Expression in Colorectal Carcinoma: An Immunohistochemical Study.
Sohag University
50 participants
May 1, 2025
OBSERVATIONAL
Conditions
Summary
Evaluation of the immunohistochemical expression of p16 in colorectal carcinoma and correlate its expression to different clinical and pathological parameters as patients' ages, sexes, tumor location, histopathological phenotype, status of nodal involvement, perineural and lymphovascular invasion.
Eligibility
Inclusion Criteria3
- Specimens from patients with colorectal cancer.
- Tissue blocks with sufficient material.
- Specimens with sufficient clinical data.
Exclusion Criteria2
- Tissue blocks with insufficient, destroyed or necrotic material.
- Specimens with insufficient clinical data.
Interventions
Immunohistochemical staining of paraffin embedded blocks of colorectal carcinoma tissues by p16 monoclonal antibodies to be evaluated with the positivity, intensity and distribution of the detected stain.
Locations(1)
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NCT07047482