RecruitingNCT07048795

Impact of the Mylife CamAPS FX System With the DEXCOM G6 Sensor on T1D Patients in France

Impact de l'Utilisation du système Mylife CamAPS FX associé au Capteur DEXCOM G6 Sur le contrôle glycémique et la qualité de Vie de Patients DT1, en Vie réelle, en France


Sponsor

mylife Diabetes Care AG

Enrollment

125 participants

Start Date

Dec 11, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

This is a non-interventional, longitudinal, prospective, multicenter, post market-registration and national study conducted in France. The study is conducted among participants with type 1 diabetes (T1D) using the mylife CamAPS FX hybrid closed-loop insulin delivery system combined with the DEXCOM G6 Continuous Glucose Monitoring (CGM) sensor (the System). The main objective of the study is to evaluate, under real-life conditions, the impact of the System on glycemic control in participants with T1D after one year of use. Secondary objectives include assessing participant-reported outcomes, such as quality-of-life, treatment satisfaction, fear of hypoglycemia, and sleep quality, describing complications related to the system, the rate of hybrid closed-loop usage over one year, and analyzing system usage parameters (e.g., Boost/Ease-Off mode use, insulin-to-carbohydrate ratios, alarms). The study will involve approximately 125 participants (including 100 adults and 25 minors) across 20 centers in France. Endocrinologists / diabetes specialists will monitor participants over the 12-month period after they start using the system and collect data at the three data collection time points.


Eligibility

Inclusion Criteria6

  • Patients with type 1 diabetes who have been using a Dexcom or Abbott Libre glucose sensor (any model) for at least 14 days prior to the date of installation of the mylife YpsoPump, with at least 70% coverage, under the same sensor.
  • Patient for whom the diabetes specialist decides to initiate the mylife CamAPS FX hybrid closed loop.
  • Patient who received the information sheets and gave their consent to participate in the study and to the processing of their personal data.
  • Adult patient who signed an informed consent form to participate in the study or minor patient whose parents signed an informed consent form for their child's participation in the study.
  • Adult patient, minor patient old enough to complete the questionnaires or parent of a minor patient able to read and understand French.
  • Adult patient / minor patient capable to complete the questionnaires or parent of a minor patient who agrees to complete the online self-questionnaires.

Exclusion Criteria9

  • Patient who used a hybrid closed-loop system, a fully closed-loop system, or a do-it-yourself loop system, regardless of the brand or model, within the past 6 months.
  • Patients participating or having participated in a clinical trial in the previous month that prevents them from participating in other studies.
  • Patient or parent unable to give consent.
  • Protected Patient (subject to a legal protection measure: guardianship, curatorship or legal safeguard).
  • Patient with a contraindication to the prescription of the mylife CamAPS FX hybrid closed-loop ( according to the Instructions For Use, IFU).
  • Patient with an unresolved skin condition in the area of sensor placement and/or in the tubing placement area (e.g. psoriasis, dermatitis herpetiformis, rash, staphylococcal infection).
  • Patient with unstable diabetic retinopathy requiring laser treatment.
  • Patient with a concomitant condition or treatment that alters glucose metabolism and that, in the investigator's judgment, is likely to have a significant impact on glycemic control;
  • Patient whose follow-up cannot be carried out by the centre (relocation planned within 12 months of inclusion).

Interventions

OTHERNo Intervention: Observational Cohort

No intervention


Locations(20)

CHU Amiens

Amiens, France

Hôtel Dieu-Pédiatrie

Angers, France

CH Victor Dupouy

Argenteuil, France

Hôpital Bois Guillaume

Bois-Guillaume, France

CHU Brest - Hôpital La Cavale Blanche

Brest, France

Hôpital Femme Mère Enfant Lyon

Bron, France

CHU Grenoble Alpes

Grenoble, France

Groupe Hospitalier de la Rochelle Ré Aunis

La Rochelle, France

Hospices Civils de Lyon DIAB-Ecare

Lyon, France

Hôpital Européen

Marseille, France

Hôpital Europeen Georges Pompidou

Paris, France

Hôpital Universitaire Necker Enfants Malades

Paris, France

Groupe hospitalier Bichat Claude Bernard

Paris, France

CH Périgueux

Périgueux, France

CHU Poitiers

Poitiers, France

Hôpital NOVO, Site Pontoise

Pontoise, France

CHU Toulouse

Toulouse, France

CHRU Nancy-Hôpitaux de Brabois Adultes

Vandœuvre-lès-Nancy, France

CH Bretagne Atlantique

Vannes, France

Hôpital Robert Schuman-UNEOS

Vantoux, France

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NCT07048795


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