RecruitingNot ApplicableNCT07050264

The Effect of Simulated Burn Injury on Post Exercise Recovery in Hot Environments


Sponsor

University of Texas Southwestern Medical Center

Enrollment

28 participants

Start Date

Mar 1, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

Burn survivors have difficulty thermoregulating due to reduced skin blood flow and sweating responses at the grafted sites. It has been previously shown that this impaired heat dissipation results in burn survivors experiencing higher core temperatures for a given exercise/environmental exposure compared to non-burned individuals. This also holds true with the use of simulated burn injury. When an absorbent material is applied to the skin over a desired amount of body surface area, it replicates a burn injury of the same size (i.e., simulated burn injury). A question that remains unknown is if this impaired thermoregulation in burn survivors would affect post-exercise core temperature recovery, i.e., do burn survivors recover slower than non-burned individuals upon stopping exercise. To that end, the primary objective of this project is to determine the rate at which body temperature and other markers of thermoregulation recover after a bout of exercise in the heat and if this response is different in the same individual with and without simulated burn injury.


Eligibility

Min Age: 18 YearsMax Age: 65 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying Simulated burn injury via application of absorbent and impermeable material over 60% of the body for people with body temperature regulation, burn injury, and other related conditions. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years to 65 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERSimulated burn injury via application of absorbent and impermeable material over 60% of the body

Simulated burn injury via application of absorbent and impermeable material over 60% of the body


Locations(1)

Institute for Exercise and Environmental Medicine - Texas Health Presbyterian Hospital Dallas

Dallas, Texas, United States

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NCT07050264


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