RecruitingNot ApplicableNCT07050537

A Multicenter Prospective Randomized Controlled Clinical Trial Comparing Constant (5%) Versus Sequential (5%-2%) Oxygen Concentration Embryo Culture Protocols in Assisted Reproductive Technology

A Multicenter Prospective Randomized Controlled Clinical Trial Comparing Constant (5%) Versus Sequential (5%-2%) Oxygen Concentration Embryo Culture Protocols in Assisted Reproductive Technology: Evaluating Term Live Birth and Offspring Health Outcomes


Sponsor

The First Affiliated Hospital with Nanjing Medical University

Enrollment

980 participants

Start Date

Mar 1, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

To evaluate whether there were significant differences in the effects of constant (5%) versus sequential (5%-2%) oxygen concentration protocols in embryo culture on term live birth rates. This study will be conducted in five centers including the Clinical Center of Reproductive Medicine, First Affiliated Hospital of Nanjing Medical Universit. 980 women who wish to undergo blastocyst transplantation will be included in the study. The study data will be analyzed statistically.


Eligibility

Sex: FEMALEMin Age: 20 YearsMax Age: 40 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a procedure called Constant oxygen concentration protocols in embryo culture and a procedure called Sequential oxygen concentration protocols in embryo culture for people with blastocyst ivf, embryo culture, and other related conditions. The study is currently recruiting participants at 5 locations.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

PROCEDUREConstant oxygen concentration protocols in embryo culture

Participants were randomly assigned to constant (5%) oxygen concentration group and received different blastocyst culture protocols.

PROCEDURESequential oxygen concentration protocols in embryo culture

Participants were randomly assigned to sequential (5%-2%) oxygen concentration group and received different blastocyst culture protocols.


Locations(6)

The Third Affiliated Hospital of Zhengzhou University

Zhengzhou, Henan, China

Changzhou Maternal And Child Health Care Hospital

Changzhou, Jiangsu, China

Nanjing Women and Children's Healthcare Hospital

Nanjing, Jiangsu, China

Reproductive Medicine of First Affiliated Hospital with Nanjing Medical University

Nanjing, Jiangsu, China

Suzhou Municipal Hospital

Suzhou, Jiangsu, China

Northwest Women's and Children's Hospital

Xi’an, Shanxi, China

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NCT07050537


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