How Healthy Are Your Oats?
Assessment of Bioaccessibility of Oat Bioactive Compounds and Contaminants in Human Volunteers
University of Aberdeen
16 participants
Jun 2, 2025
INTERVENTIONAL
Conditions
Summary
Oat foods are commonly consumed as healthy breakfast options and their nutritional value is well recognised. Oats are a rich source of fibre, micronutrients and non-nutrient bioactive compounds, but at the same time cereals including oats can be contaminated with mycotoxins. To fully understand the nutritional benefits and potential food safety risks of oat consumption, this study aims to assess the nutritional composition of an oat food and the bioavailability of bioactive oat constituents and their metabolite profile in urine of volunteers consuming a single portion of an oat breakfast. This study requires 16 healthy volunteers to consume one portion of oats and collect their urine over 48 hours after the test meal. No other sample collection is required.
Eligibility
Inclusion Criteria1
- Adult males and females (aged 18 - 65 years) who are healthy with a BMI in the normal to overweight range (18.5-29.9)
Exclusion Criteria10
- Anyone who currently suffers from gastrointestinal or metabolic diseases, liver disease or kidney disease
- Anyone who currently has an eating disorder (anorexia, bulimia, binge eating, night eating syndrome)
- Anyone who is taking prescribed medication related to gastrointestinal, metabolic, liver or kidney disease
- Anyone who has taken antibiotics in the past 3 months
- Anyone who is allergic or intolerant to oat foods
- Anyone who is currently pregnant or breastfeeding
- Anyone who is currently taking vitamin or mineral supplements (unless they agree to discontinue supplementation 2 weeks before the study)
- Anyone currently participating in another research study
- Anyone who is unable to fluently speak, read and understand English
- Anyone who is unable to give written informed consent
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Interventions
Single dose of commercially available Oat food test meal
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT07050680