RecruitingEarly Phase 1NCT07053358

Safety and Efficacy Evaluation of LX111 Gene Therapy in nAMD Patients

An Exploratory Clinical Study Evaluating LX111 Gene Therapy in Patients With Neovascular Age-related Macular Degeneration (nAMD)


Sponsor

Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine

Enrollment

10 participants

Start Date

Jul 2, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

The goal of this study is to evaluate the safety and efficacy of LX111 treatment of nAMD. This study will enroll subjects aged ≥ 50 vears old to receive a single unilateral intravitreal (lVT) injection of LX111 to evaluate its safety and efficacy.


Eligibility

Min Age: 50 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying LX111 Injection for people with neovascular age-related macular degeneration. The study is currently recruiting participants at 1 location. People eligible for this study include aged 50 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

GENETICLX111 Injection

Qualified subjects will receive a single unilateral intravitreal injection of LX111 at Day 0.


Locations(1)

Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine

Shanghai, China

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NCT07053358


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