RecruitingNot ApplicableNCT07056582

Pre-emptive Analgesia Using Nebulized Ketamine Versus Nebulized Dexmedetomidine in Endoscopic Nasal Surgeries


Sponsor

Sohag University

Enrollment

105 participants

Start Date

Apr 14, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

this study aims to compare the efficacy of pre-emptive nebulized ketamine versus nebulized dexmedetomidine for post operative pain relief in endoscopic nasal surgery


Eligibility

Min Age: 20 YearsMax Age: 60 Years

Inclusion Criteria4

  • patients between the ages of 20 and 60,
  • both sexes,
  • American Society of Anesthesiologists physical status I to II
  • BMI ≥18≤30 kg/m²

Exclusion Criteria5

  • Patient refusal.
  • patients with advanced respiratory, renal, hepatic, neurological, or psychiatric disease, pregnant or nursing women.
  • patients with a history of allergies to any study drugs.
  • patients who had used central nervous system depressants or analgesics within the previous 24 hours.
  • patients with hypertension, hypotension, or bradycardia.

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Interventions

DRUGDexmedetomidine

patients in this group will receive nebulized Dexmedetomidine before onset of surgery

DRUGKetamine

patients in this group will receive nebulized ketamine before onset of surgery

DRUG0.9%sodium chloride

patients in this group will receive nebulized 0.9% normal saline before onset of surgery


Locations(1)

Sohag university hospital

Sohag, Egypt

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NCT07056582