RecruitingNot ApplicableNCT07057544

UHF ECG in LBBB and Response to CRT Prediction

The Role of Ultra-high-frequency ECG in the Localization of Left Ventricular Conduction Disorders and Prediction of Response to Resynchronization Therapy


Sponsor

Faculty Hospital Kralovske Vinohrady

Enrollment

200 participants

Start Date

May 1, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

The main objective of the project is to demonstrate that in patients with heart failure and QRS complex of nonRBBB morphology lasting over 130 ms, UHF-ECG can differentiate patients with trueLBBB from IVCD better than existing approaches based on the assessment of QRS complex morphology and duration from 12-lead ECG. Another goal of the proposed study is to demonstrate that trueLBBB patients will benefit more from CRT using left bundle branch pacing than from CRT using biventricular pacing. The final aim of the project is to demonstrate that the echocardiographic and clinical response in patients with intraventricular conduction disturbance will be dependent on the degree of reduction in ventricular dyssynchrony after CRT.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a medical device called BVP-CRT and LBBAP CRT device implantation for people with biventricular pacing, intraventricular conduction delay, and other related conditions. The study is currently recruiting participants at 1 location.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DEVICELBBAP CRT device implantation

Pacing system with a lead implanted in the left bundle branch area will be done.

DEVICEBVP-CRT

Implantation of biventricular device


Locations(1)

Faculty Hospital Kralovske Vinohrady

Prague, Česká Republika, Czechia

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NCT07057544


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