RecruitingNCT07063043
Clinical Research on 68Ga-FAPI PET/CMR in Cardiovascular Diseases
Sponsor
Shanghai East Hospital
Enrollment
40 participants
Start Date
Dec 1, 2024
Study Type
OBSERVATIONAL
Conditions
Summary
FAP-targeted PET imaging using 68Ga-FAPI enables early detection of myocardial fibrosis. Combined PET/CMR provides comprehensive cardiac assessment without extra radiation. This advanced imaging approach improves diagnosis and personalized treatment for better patient outcomes.
Eligibility
Min Age: 18 Years
Inclusion Criteria4
- Participants must have a confirmed clinical diagnosis of cardiovascular disease by a cardiologist, based on genetic testing, family history, and comprehensive clinical evaluation including physical examination, echocardiography, and when indicated, cardiac MRI findings.
- Age requirement: >18 years.
- Patients should demonstrate stable cardiovascular status without significant changes in symptoms, treatment, or clinical findings for a specified pre-enrollment period.
- Participants must be capable of providing informed consent and willing to adhere to all study requirements, including follow-up procedures.
Exclusion Criteria7
- History of malignancy
- Documented cardiovascular diseases, including coronary artery disease, myocardial infarction, or related conditions
- Implanted metallic devices (e.g., pacemakers, aneurysm clips) or other MRI-incompatible medical prostheses
- Claustrophobia
- Pregnancy or lactation
- Known hypersensitivity to gadolinium-based contrast agents
- Renal impairment (eGFR <30 mL/min/1.73m² by CKD-EPI equation)
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Locations(1)
View Full Details on ClinicalTrials.gov
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NCT07063043
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