RecruitingNot ApplicableNCT07063732

Ketone Monoester Supplements, High Altitude, and Brain Blood Flow During Exercise

The Effect of Ketone Monoester Supplementation and High Altitude on Exercising Cerebral Blood Flow


Sponsor

McMaster University

Enrollment

14 participants

Start Date

May 28, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

The purpose of this trial is to investigate the effect of acute ketone monoester ingestion (0.6 g KME/kg body weight) on the occurrence of the ventilatory threshold and the subsequent response of blood velocity in cerebral arteries during a maximal exercise test at low altitude and high altitude.


Eligibility

Min Age: 18 YearsMax Age: 35 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying Ketone Monoester (KME) and Placebo for people with exercise and high altitude hypoxia. The study is currently recruiting participants at 2 locations. People eligible for this study include aged 18 Years to 35 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DIETARY_SUPPLEMENTKetone Monoester (KME)

0.6 g KME per kg body mass; \[R\]-3-hydroxybutyl \[R\]-3-hydroxybutyrate. (Delta G Ketone, TΔS, Oxford).

DIETARY_SUPPLEMENTPlacebo

Inert, calorie-free placebo drink that is taste-matched to the ketone monoester supplement


Locations(2)

Barcroft Research Station

Bishop, California, United States

University of Guelph

Guelph, Ontario, Canada

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NCT07063732


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