RecruitingPhase 1NCT07065682

Effetivity of Dutasteride and Aloe Vera Extract Combination on Angiogenesis and Obstruction on Benign Prostatic Hyperplasia

Sponsor

Universitas Diponegoro

Enrollment

84 participants

Start Date

Jul 1, 2023

Study Type

INTERVENTIONAL

Conditions

BPH (Benign Prostatic Hyperplasia)

Summary

This study is a double blinded RCT with pre-post test design on the effect of combination of dutasteride and aloe vera, compared to dutasteride only, on uroflowmetry results, prostate volume, and VEGF serum level among patients with benign prostate hyperplasia. The treatment was given for 12 weeks

Eligibility

Sex: MALEMin Age: 50 Years

Inclusion Criteria2

Diagnosed with BPH clinically or radiologically (prostate volume \> 30 gram, Qmax \<15 mL/s)
Willing to participate to the study

Exclusion Criteria6

Clinically or radiologically suspected of having prostatic cancer
Previous prostatic surgery
Patients with urinary retention
Patients with BPH complications: urinary tract infections, urolithiasis, or hydroneprhosis
Previously consumed alpha blocker or 5ARI in the last 6 months
Have consumed aloe vera extract routinely

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