Quantification & Classification of Inflammatory Cells in Uveitis Using OCT
Objective Grading of Intraocular Inflammation in Uveitis Using Optical Coherence Tomography
Oregon Health and Science University
125 participants
Sep 1, 2024
OBSERVATIONAL
Conditions
Summary
The goal of this study is to determine if it's possible to use a high resolution imaging device called optical coherence tomography (OCT) to develop an unbiased, standard method of counting and categorizing the various types of cells and proteins found in an eye condition called anterior uveitis. Anterior uveitis is a type of inflammation in the eye that can be caused by many different diseases of the body.
Eligibility
Inclusion Criteria3
- Uveitis Group: Eyes with active intraocular inflammation and a clinical diagnose of spondyloarthritis/HLA-B27 associated anterior uveitis, Juvenile Idiopathic Arthritis (JIA) associated chronic anterior uveitis, Herpes Simplex Virus (HSV) anterior uveitis, Birdshot chorioretinitis, Behcet disease uveitis, sarcoidosis associated uveitis, uveitis of any additional type, or uveitis masquerade.
- Posterior Vitreous Detachment Group: Eyes with vitreous floaters and posterior vitreous detachment (PVD).
- Healthy/Control Group: Healthy eyes with no history of uveitis, PVD, or previous eye surgery.
Exclusion Criteria4
- Inability to give informed consent.
- Inability to maintain stable fixation for OCT imaging.
- Inability to commit to required visits to complete the study.
- Pregnancy and breastfeeding.
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Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT07065747