RecruitingNot ApplicableNCT07068204

Comparative Study of Caries-Preventive Effects: 2% Calcium Hypophosphite Toothpaste vs. Sodium Fluoride Toothpaste (1450ppm F)

Caries-preventing Effect of 2% Calcium Hypophosphite Toothpaste Compared to a Sodium Fluoride Toothpaste (1450ppm F) in Adults

Sponsor

Dr. Joachim Enax

Enrollment

164 participants

Start Date

Jan 22, 2026

Study Type

INTERVENTIONAL

Conditions

Caries,Dental Calcium Hypophosphite Fluoridation

Summary

The aim of the study is to compare the caries-preventive effect of the test and control toothpaste in order to proof the non-inferiority of the test toothpaste compared to the control.

Eligibility

Min Age: 18 YearsMax Age: 45 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a medical device called 2% Calcium Hypophosphite Toothpaste and a medical device called Sodium Fluoride Toothpaste (1450 ppm F) for people with calcium hypophosphite, caries,dental, and other related conditions. The study is currently recruiting participants at 2 locations. People eligible for this study include aged 18 Years to 45 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DEVICE2% Calcium Hypophosphite Toothpaste

Oral hygiene instruction and regular application of the 2% Calcium Hypophosphite Toothpaste at home (twice daily over a period of 546 days, i.e., 18 months).

DEVICESodium Fluoride Toothpaste (1450 ppm F)

Oral hygiene instruction and regular application of the Sodium Fluoride Toothpaste at home (twice daily over a period of 546 days, i.e., 18 months).