RecruitingNot ApplicableNCT07069374

Wellness, Intervention Strategies and HIV Care


Sponsor

University of California, San Francisco

Enrollment

50 participants

Start Date

Sep 1, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

This is a pilot trial designed to assess the feasibility and acceptability of an intervention aimed at improving adherence to antiretroviral therapy (ART), viral suppression, and engagement in HIV care. The intervention will address behavioral coping strategies, HIV care engagement behaviors, and substance use management.


Eligibility

Sex: FEMALEMin Age: 18 Years

Inclusion Criteria19

  • • Participants must:
  • Be at least 18 years of age
  • Self-report biological characteristics consistent with the population under study
  • Be HIV-positive
  • Report use of at least one of the following substances in the last 90 days:
  • Cannabis
  • Methamphetamine
  • Cocaine/crack
  • Cocaine
  • Heroin
  • Non-prescribed opioids (e.g., fentanyl, morphine)
  • Ecstasy
  • Phencyclidine (PCP)
  • Psychedelics (e.g., Lysergic acid diethylamide, mescaline, ketamine)
  • Poppers (alkyl nitrites)
  • Non-prescribed benzodiazepines (e.g., Valium, Xanax, Klonopin, Librium)
  • Barbiturates
  • Be English-speaking
  • Be able and willing to provide informed consent

Exclusion Criteria2

  • Evidence of severe cognitive impairment or active psychosis that may impede ability to provide fully informed consent, determined by the research assistants and clinical supervisor(s)
  • The research staff are trained on guidelines for identifying participants who exhibit signs of inability to meaningfully participate or provide consent due to mental illness or impairment

Interventions

BEHAVIORALWellness, Intervention Strategies and HIV Care (WISH)

A structured behavioral group program consisting of five weekly sessions, each approximately 60-90 minutes in length. The intervention is designed for individuals living with HIV who use substances and focuses on: managing stress, addressing barriers to care, and enhancing engagement with HIV-related health services. Sessions are delivered in a small-group format and facilitated by trained staff using a manualized curriculum.

BEHAVIORALMovie Night Club - Attention and Time Matched Control

Weekly 90-minute group sessions over 5 weeks in which participants watch non-therapeutic, neutral-content movies in a group setting. Sessions are facilitated to control for social interaction and time spent in a structured group environment but do not include any therapeutic content.


Locations(2)

Oakland MWCCS Site Office

Oakland, California, United States

SF MWCCS Site Office

San Francisco, California, United States

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NCT07069374


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