RecruitingPhase 2NCT07073287

Efficacy of Cerebello-spinal Direct Current Stimulation (csDCS) on Functional Mobility in Chronic Stroke Patients

Efficacy of Cerebello-spinal Direct Current Stimulation on Functional Mobility in Chronic Stroke Patients


Sponsor

Universidade Federal de Pernambuco

Enrollment

30 participants

Start Date

May 1, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

The aim of this clinical trial is to determine if cerebello-spinal direct current stimulation (csDCS) is effective in treating gait disorders in individuals with chronic stroke. Additionally, the trial seeks to evaluate the safety of this technique. The primary objectives include: Investigating whether cerebello-spinal direct current stimulation improves gait and functional mobility in participants with chronic stroke. Assessing any potential side effects associated with the method. Researchers will conduct a comparative analysis between cerebello-spinal direct current stimulation and a sham procedure (which mimics the stimulation without any actual effect) to assess its effectiveness in addressing gait disorders and enhancing mobility. Participants in the trial will: Undergo cerebello-spinal direct current stimulation combined with treadmill training or a sham procedure with treadmill training daily over a two-week period.


Eligibility

Min Age: 18 YearsMax Age: 75 Years

Inclusion Criteria3

  • Confirmation of Stroke by digital or physical imaging or medical report
  • Gait impairment
  • Stroke with at least 6 months after ictus

Exclusion Criteria3

  • Metallic implants in spinal cord
  • Major orthopedic/rheumatological disorders
  • Inability of verbal or non-verbal communication

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Interventions

DEVICECerebello-spinal direct current stimulation

csDCS influences both ascending and descending spinal pathways and reflex excitability, promoting prolonged functional neuroplastic changes.

DEVICESham Comparator

Masking for cerebello-spinal direct current stimulation involves the electric current stopping after 30 seconds, providing a sensation without producing neuromodulation.


Locations(3)

Federal University of Paraiba

João Pessoa, Paraíba, Brazil

Federal University of Pernambuco

Recife, Pernambuco, Brazil

Federal University of Rio de Janeiro

Rio de Janeiro, Rio de Janeiro, Brazil

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NCT07073287


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