Mobile Health Intervention to Improve Adherence to Oral Anticancer Therapy
Mobile Health Intervention to Improve Adherence to Oral Anticancer Therapy: A Pilot Feasibility Clinical Trial
University of California, Irvine
35 participants
Aug 26, 2025
INTERVENTIONAL
Conditions
Summary
New oral anticancer treatments have improved survival across cancer types but introduced challenges in medication adherence and symptom management. The SMART pilot trial will test a new mobile health intervention that facilitates remote adherence and symptom monitoring, patient-provider communication outside of clinic visits regarding the use of oral anticancer treatments, and support for financial and social needs, as well as health literacy support, for 30 English- and Spanish-speaking patients. This study will increase understanding of barriers and facilitators to the use of the proposed mHealth intervention.
Eligibility
Inclusion Criteria6
- Must speak English or Spanish
- Must be 18 years of age or older
- Have a diagnosis of any type and stage of cancer
- Have a new prescription for an oral anticancer therapy (OAT) initiated within the last 90 days or planned to start within the next 15 days
- Be receiving treatment at UCI Chao Family Comprehensive Cancer Center-affiliated oncology clinics
- Own a smartphone and be willing to receive study-related text messages.
Exclusion Criteria3
- Have an Eastern Cooperative Oncology Group (ECOG) performance status greater than 2
- Be medically or cognitively unable to give consent or participate in the study
- Be participating in another clinical trial that monitors adherence or symptoms related to the newly prescribed OAT
Interested in this trial?
Get notified about updates and connect with the research team.
Interventions
The SMART intervention uses TAPPT® smart labels and a web-based app for real-time monitoring of oral anticancer therapy adherence. It includes personalized text reminders, biweekly surveys for medication adherence and symptom burden, missed and extra dose management, symptom alerts to providers, monthly financial and health-related social needs screening with tailored resources, and educational texts for low health literacy. TAPPT® smart labels work with Android/iOS smartphones. All participants receive usual oncology care.
Locations(5)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT07073807