Observational Study to Describe Health-Related Quality of Life and Measure Disease Burden Among Patients With Long QT Syndrome Types (LQTS) 2 and 3

Inclusion Criteria9

• The participant is willing and provides written informed consent to participate in this study.
• Male or female participant of at least 18 years of age, English-speaking.
• Confirmed genetic diagnosis of LQT2 or 3, demonstrated by one of the following:
• Genetic testing report (pathogenic or likely pathogenic (P/LP) mutation) in KCHN2 or SCN5a genes) or,
• A signed physician's letter confirming genetic diagnosis of LQTS 2 or 3.
• Documented QTc ≥ 480 ms within the last year, demonstrated by one of the following:
• -lead electrocardiogram (ECG), or
• A signed physician's letter confirming an ECG demonstrating QTc value ≥ 480 ms.
• The participant is able to operate a smartphone and a companion watch. *The number of participants with QTc between 480 and 500 ms will be limited to 50.