The Effect of Multimodal Pain Regimen on Use of Narcotics After Rotator Cuff Tear Repair
Montefiore Medical Center
130 participants
Jul 21, 2025
INTERVENTIONAL
Conditions
Summary
The goal of this clinical trial is to understand which group of pain control medications work best in adults after rotator cuff surgery.
Eligibility
Inclusion Criteria1
- Adults with rotator cuff tears who have failed conservative therapy and are now undergoing arthroscopic rotator cuff repair.
Exclusion Criteria7
- Patients without capacity to consent for the study
- Patients not able to have local nerve block
- Patients who underwent previous shoulder surgery on the same side, kindling revision rotator cuff repair
- Patients who are unable to record and verbalize their pain level due to altered mental status
- Patients who are unable to tolerate any of the medications included in the multimodal pain regimen or standard pain regimen due to severe allergies or inability to consume medication
- Patients with history of previously diagnosed alcohol or drug abuse, renal impairment, peptic ulcer disease, and gastrointestinal bleeding
- Patients who are pregnant
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Interventions
Preoperatively: One dose of Pregabalin 100mg and Celecoxib 400mg along with interscalene block Intraoperatively: Intravenous Dexamethasone 0.1mg/kg (maximum dose of 8mg), Magnesium 2g, Acetaminophen 1000mg, and local infiltration of 0.5% Ropivacaine 20ml Postoperatively (Discharge): Acetaminophen 975mg every 4 hours, Meloxicam 7.5mg once per day, Pregabalin 50mg twice per day, Magnesium 400mg once per day, along with rescue Oxycodone 5mg every 4 hours, as needed
No preoperative medications. Interscalene block in the preoperative holding area. Alternating Acetaminophen 975mg and Ibuprofen 600mg every 4 hours, with rescue Oxycodone 5mg every 4 hours, as needed
Locations(1)
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NCT07076069