RecruitingPhase 2NCT07208799

Comparison of Submucosal Dexamethasone and Methylprednisolone in Postoperative Sequelae of Parasymphsis Fractures

Comparison of Effectiveness of Submucosal Dexamethasone and Methylprednisolone in Management of Postoperative Sequelae in Mandibular Parasymphysis Fractures


Sponsor

Nishtar Medical University

Enrollment

72 participants

Start Date

Jan 3, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

The rationale of the current research is to address the limitation of existing knowledge as it is not clear which of the two drugs (Dexamethasone or Methylprednisolone) is more effective in reduction of postoperative sequelae in patient with mandibular parasymphysis fracture. This study fills the gap by providing sound evidence on the preferred steroid option to help clinicians have more data to make decisions and improve patients' health. The result of this research will then be added to the evidence-based protocols for the treatment of parasymphysis fractures.


Eligibility

Min Age: 18 YearsMax Age: 40 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Dexamethasone and a drug called Methylprednisolone (Corticosteroid) for people with corticosteroid injection, edema face, and other related conditions. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years to 40 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGDexamethasone

single dose of dexamethasone 8 mg (2 mL) administered submucosally at the surgical site 30 minutes before incision.

DRUGMethylprednisolone (Corticosteroid)

a single dose of methylprednisolone 40 mg (2 mL) will be administered submucosally at the surgical site 30 minutes before incision.


Locations(1)

Nishtar Institute of Dentistry Multan

Multan, Punjab Province, Pakistan

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NCT07208799


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