Effect of Pre-delivery Dexamethasone in Comparison With Betamethasone on Fetal Heart Trace
Comparison of Effect of Antenatal Dexamethasone Versus Betamethasone on Antepartum Cardiactocography
Rawalpindi Medical College
110 participants
Jul 13, 2025
INTERVENTIONAL
Conditions
Summary
As baby grows inside the womb of mother, heart and other organs develop. The heart activity can be recorded by placing a transducer on the belly of mother. The tracing obtain provides information about heart rate, any increase or decrease in heart rate and how much it varies with time. Variation in heart rate along with increase is indicator of fetal well being. Some mothers are at high risk of pre-term birth that is baby delivery before 37 weeks of gestation. In such cases steroids are given to mother to accelerate lung development of the baby so that it can easily adapt to outside world. Dexamethasone and Betamethasone are commonly used steroids which can also effect fetal heart activity.
Eligibility
Inclusion Criteria3
- History of pre term labor
- Preterm pre labor rupture of membranes
- Third trimester bleeding due to placenta previa
Exclusion Criteria6
- IUGR
- Uteroplacental insufficiency
- Oligohydroamnios
- Maternal drug therapy that can effect fetal heart rate
- Contraindications to Intramuscular injections
- Patients admitted with non reassuring CTG
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Interventions
Intramuscular injection of Betamethasone 12mg will be administered on 2 consecutive days
two doses of 12mg of IM Dexamethasone given 24 hours apart
Locations(1)
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NCT07078786