RecruitingNCT07079774

TrueLok Elevate PMCF Study

Post-Market Clinical Follow-up Study of the TrueLok Elevate Transverse Bone Transport System for the Treatment of Lower Limb Ulcers as Soft Tissue Defects


Sponsor

Orthofix s.r.l.

Enrollment

153 participants

Start Date

Nov 24, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

The TrueLok Elevate Transverse Bone Transport System is a modular external fixation device designed for transverse bone transport. It promotes local vascular and wound healing through controlled corticotomy and gradual distraction. The system is intended for adult patients with bony and/or soft tissuedefects.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a medical device called Transverse Bone Transport System for people with soft tissue defect, ulcers, and other related conditions. The study is currently recruiting participants at 5 locations. People eligible for this study include aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DEVICETransverse Bone Transport System

This is a prospective, international, multicentre, observational post-market clinical follow-up (PMCF) study. Adult subjects will be treated according to the manufacturer's Instructions for Use, with follow-up extending to 12 months post-device removal. Participating sites include centres in the US, Europe, the UK, and South Africa. Subjects will be followed using a phased framework: T0: Index Surgery (baseline data, operative details, ulcer status) T1: End of Distraction (device parameters, adverse events, ulcer status) T2: End of Compression (similar to T1) T3: Device Removal (confirmation of union, ulcer status) Post-removal visits: F3: 3 months F6: 6 months F12: 12 months


Locations(5)

Helios Klinikum Wuppertal GmbH

Wuppertal, Germany

General Regional Hospital F. Miulli of Acquaviva delle Fonti

Acquaviva delle Fonti, Bari, Italy

Stellenbosch University

Cape Town, Western Cape, South Africa

Hospital de la Santa Creu i Sant Pau

Barcelona, Spain

Hull University Teaching Hospitals NHS Trust

Hull, Hull, United Kingdom

View Full Details on ClinicalTrials.gov

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NCT07079774


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