RecruitingPhase 4NCT07084441

Comparison of Outcomes of Management of Bowel Obstruction


Sponsor

University of Washington

Enrollment

550 participants

Start Date

Feb 3, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

The Comparison of Outcomes of Management of Bowel Obstruction (COMBO) trial is a patient-level randomized trial of a short course of dexamethasone + supportive care vs supportive care alone for patients with adhesion-related small bowel obstruction (aSBO). The goal of the COMBO trial is to answer the question: Can Dexamethasone increases the proportion of patients with resolution of aSBO with non-operative management (without complication) based on an established minimal important clinical difference.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Dexamethasone and Supportive Care for people with adhesive small bowel obstruction. The study is currently recruiting participants at 4 locations. People eligible for this study include aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGDexamethasone

\*Please see description for dexamethasone + supportive care arm.

OTHERSupportive Care

\*Please see description for supportive care arm.


Locations(4)

Columbia University Medical Center

New York, New York, United States

Harborview Medical Center

Seattle, Washington, United States

UW Medical Center - Northwest

Seattle, Washington, United States

University of Washington Medical Center Montlake

Seattle, Washington, United States

View Full Details on ClinicalTrials.gov

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NCT07084441


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