RecruitingNot ApplicableNCT07086131

A Study Investigating the Impact of IMT With CR On Exercise Responses In HF

Impact Of Adding Inspiratory Muscle Training To Cardiac Rehabilitation On Exercise Responses In Heart Failure


Sponsor

Mayo Clinic

Enrollment

70 participants

Start Date

Sep 4, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

The purpose of this study is to compare the impact of inspiratory muscle training (IMT) combined with cardiac rehabilitation (CR) on cardiovascular function in patients with heart failure.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is testing whether a breathing muscle training technique called Inspiratory Muscle Training (IMT) combined with controlled carbon dioxide rebreathing can improve exercise tolerance and reduce breathlessness in patients with heart failure with reduced ejection fraction (HFrEF) — a type of heart failure where the heart does not pump enough blood. **You may be eligible if...** - You are 18 or older - You have been diagnosed with HFrEF and are on stable heart medication for at least 6 weeks - Your heart failure symptoms are mild to moderate (NYHA Class I to III) - You have not been hospitalized in the last 3 months - Your BMI is 45 or below and you are a non-smoker with fewer than 30 pack-years of smoking history - You are physically able to exercise without major orthopedic limitations **You may NOT be eligible if...** - You have had dangerous heart rhythm problems within the last 21 days - You have a second or third-degree heart block - You are a current smoker or have a heavy smoking history - Your BMI is above 45 Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DEVICEPowerbreathe

The breathing training will consist of using the PowerBreathe for 12 weeks. The PowerBreathe is an inspiratory pressure threshold trainer. The valve blocks the airflow until the threshold pressure is achieved by breathing in forcefully into the device.


Locations(1)

Mayo Clinic in Rochester

Rochester, Minnesota, United States

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NCT07086131


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