Sleep Apnea Triggers of Atrial Fibrillation: N-of-1 Randomized Control Trial (SPARTA):

This study (SPARTA) investigates whether treating sleep apnea — a condition where breathing repeatedly stops during sleep — can reduce episodes of atrial fibrillation (an irregular heart rhythm). It uses an N-of-1 design, meaning each participant acts as their own control at different times. **You may be eligible if...** - You are between 18 and 85 years old - You have frequent episodes of paroxysmal atrial fibrillation (AF occurring in bursts, ≥1% burden) - You have been diagnosed with moderate-to-severe sleep apnea (AHI ≥ 15) - You have an implanted cardiac device that tracks heart rhythms - You are enrolled in remote cardiac monitoring **You may NOT be eligible if...** - You had AF ablation (procedure to correct AF) within the past 6 months - You have significant heart valve problems - You have severe daytime sleepiness that makes CPAP medically necessary right away Talk to your doctor to see if this trial is right for you.