RecruitingNCT07089277

External Validation of the Glasgow-Blatchford Bleeding Score in a Tunisian Population


Sponsor

Hôpital Universitaire Sahloul

Enrollment

250 participants

Start Date

Jan 1, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

This study aims to externally validate the Glasgow-Blatchford Score (GBS) in a Tunisian population presenting with non-traumatic upper gastrointestinal bleeding. Despite advances in endoscopic management, early risk stratification remains essential to guide clinical decision-making. In Tunisia, the routine hospitalization of all patients for observation presents a challenge, highlighting the need for reliable prognostic tools. The study is designed as a multicenter, descriptive, and analytical investigation across several emergency departments. Adult patients (≥16 years) will be included, with follow-up conducted at 30 days to assess for adverse outcomes including rebleeding, the need for hemostasis, complications, and mortality. Clinical and epidemiological data will be collected using a standardized form. Statistical analysis will evaluate the predictive performance of the GBS, focusing on sensitivity, specificity, and predictive values for 30-day outcomes. The results are expected to determine whether GBS is a valid and useful tool for risk assessment in the Tunisian context, potentially aiding in more efficient and targeted patient management.


Eligibility

Min Age: 18 Years

Inclusion Criteria1

  • Adult patients (≥18 years) presenting with non-traumatic upper gastrointestinal bleeding

Exclusion Criteria3

  • patients under 18 years of age.
  • Diagnosis of external hemorrhoids with mucosal lesions.
  • Patients who do not consent, are lost to follow-up, or have incomplete data.

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Locations(1)

Sahloul University Hospital

Sousse, Tunisia

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NCT07089277


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