RecruitingNCT07090460

Pulmonary Overdistension Assessment With Electrical Impedance Tomography in Patients With Acute Respiratory Distress Syndrom in Prone Position.

Sponsor

Centre Hospitalier de la côte Basque

Enrollment

30 participants

Start Date

Nov 22, 2025

Study Type

OBSERVATIONAL

Conditions

Acute Respiratory Distress Syndrome (ARDS)

Summary

Mechanical ventilation in COPD requires a good interaction Patient-Ventilator without asynchronies in order to reduce mortality. Dynamic hyperinflation with PEEPi is responsible for major asynchronies in COPD. It is supposed to be symmetrical between the 2 lungs with the same PEEPi. EIT can measure the distribution of tidal ventilation and interlung lung insufflation delay on the impedance time curve of each lung. Moreover, it is possible in intubated COPD patients to assess one lung PEEPi during low flow insufflation with pressure-EIT monitoring. This study aims to measure interlungs insufflation delay under mechanical ventilation in COPD patients

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study uses a tool called electrical impedance tomography (EIT) — a non-invasive monitor strapped around the chest — to measure lung overdistension (over-inflation from mechanical ventilation) in patients in the ICU with severe lung disease (ARDS or severe COPD), particularly when they are placed on their stomach (prone positioning) to help their breathing. **You may be eligible if...** - You are 18 or older - You are hospitalized in the ICU - You have moderate or severe COPD (GOLD stage 3 or 4) with breathing failure, on non-invasive or invasive ventilation - You are being monitored with EIT **You may NOT be eligible if...** - You have an air leak between the lung and chest (broncho-pleural fistula) - You are pregnant or breastfeeding - You are under legal guardianship or do not have health insurance (French requirement) - EIT equipment cannot be correctly positioned Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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