RecruitingNCT07091019

A Real-world Chronic Myelogenous Leukemia (CML) Patient Disease Registry to Describe Patient Experience and Clinical Outcomes Among Patients With CML Receiving Approved First or Second Line Tyrosine Kinase Inhibitor (TKI) Therapy


Sponsor

Novartis Pharmaceuticals

Enrollment

1,000 participants

Start Date

Dec 17, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

This CML disease registry (ASC4REAL-2) aims to gather evidence on the tolerability, safety, effectiveness, and patient-reported outcomes (PRO) in real-world healthcare from patients with Ph+-CML-CP treated with TKIs approved for 1L and 2L, including prospective follow-up for 5 years identifying and describing long-term treatment outcomes.


Eligibility

Min Age: 18 YearsMax Age: 100 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying TKIs for people with chronic myelogenous leukemia - chronic phase. The study is currently recruiting participants at 15 locations. People eligible for this study include aged 18 Years to 100 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERTKIs

There is no treatment allocation for NIS trials. Patients administered TKI (asciminib, bosutinib, dasatinib, imatinib, nilotinib) by prescription will be enrolled.


Locations(17)

University of Alabama at Birmingham

Birmingham, Alabama, United States

Stockton Hematology Oncology Medical Group Inc

Stockton, California, United States

Lundquist Inst BioMed at Harbor

Torrance, California, United States

Stamford Hospital

Stamford, Connecticut, United States

Sacred Heart Medical Oncology

Pensacola, Florida, United States

Cancer Care Specialists of Central Illinois

Decatur, Illinois, United States

St Agnes Hospital

Baltimore, Maryland, United States

Truman Medical Center

Kansas City, Missouri, United States

NY Cancer and Blood Specialists

East Setauket, New York, United States

SUNY Upstate Medical University

Syracuse, New York, United States

Tri-County Hematology and Oncology Associates

Canton, Ohio, United States

Oregon Oncology Specialists Salem

Salem, Oregon, United States

Avera Cancer

Sioux Falls, South Dakota, United States

Baylor Scott and White Research

Temple, Texas, United States

Fred Hutchinson Cancer Research Center

Seattle, Washington, United States

MultiCare Health System Institute

Tacoma, Washington, United States

Northwest Medical Specialties

Tacoma, Washington, United States

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

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NCT07091019


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