RecruitingNCT07091526

Whether Control of Serum Uric Acid (SUA) Improves Survival After Pancreatic Cancer

Whether Controlling Serum Uric Acid (SUA) Can Benefit Postoperative Survival in Patients With Pancreatic Cancer


Sponsor

Hepatopancreatobiliary Surgery Institute of Gansu Province

Enrollment

168 participants

Start Date

Jul 29, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

This retrospective study aims to analyze the impact of postoperative changes in serum uric acid (SUA) levels on the prognosis of patients undergoing pancreatic cancer resection.


Eligibility

Min Age: 18 YearsMax Age: 85 Years

Inclusion Criteria3

  • Patients with pathologically confirmed pancreatic cancer (primary)
  • Patients who underwent Radical resection of pancreatic cancer(Pancreaticoduodenectomy or Distal pancreatectomy)
  • The postoperative survival time was at least 6 weeks

Exclusion Criteria14

  • No surgery was performed, or only palliative surgery/ biopsy was performed
  • Patients who underwent emergency hemodialysis or plasma exchange after surgery
  • History of gout or long-term urate-lowering therapy, such as allopurinol
  • Patients are missing follow-up data
  • Hydrochlorothiazide and furosemide were used
  • Chronic kidney disease
  • Oncolytic syndrome
  • Hemolytic anemia
  • Lead poisoning
  • Hyperparathyroidism
  • Hypothyroidism
  • A tyrosinase inhibitor was used
  • Patients with nonpancreatic primary tumors
  • Pregnant or postpartum women.

Interventions

DIAGNOSTIC_TESTserum uric acid test

Detect the serum uric acid in blood sample


Locations(1)

Hepatopancreatobiliary Surgery Institute of Gansu Province

Lanzhou, Gansu, China

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NCT07091526