RecruitingNot ApplicableNCT07091617

Testing an Enhanced Digital Delivery Model for Inherited Cancer Genetic Testing in Young Adults With Cancer

AYA Access Study: An Enhanced eHealth and Chat-Bot Enabled Delivery Model for Clinical Genetic Services in Community AYA Cancer Patients

Sponsor

Alliance for Clinical Trials in Oncology

Enrollment

535 participants

Start Date

Dec 10, 2025

Study Type

INTERVENTIONAL

Conditions

Miscellaneous Neoplasm, NOS Non-Neoplastic Condition, Nos

Summary

This phase III trial compares the use of a digital chatbot enabled intervention to standard remote genetic services for increasing uptake of genetic counseling and testing among adolescents and young adult (AYA) cancer patients. Genetic testing for cancer predisposition syndromes has become standard evidence-based practice and can inform enhanced screening and risk reducing measures to reduce cancer morbidity and mortality. Despite this, many AYAs are not receiving recommended genetic counseling and testing. Offering remote telehealth services can address access barriers and chatbots and texting interventions could enhance patient outcomes and reduce provider and staff time. The use of a digital chatbot enabled intervention may be equally as effective as standard remote genetic services in AYA cancer patients undergoing genetic testing.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study tests a digital model for delivering hereditary cancer genetic testing and counseling to young adults (ages 18–39) with cancer. The goal is to make genetic testing more accessible, especially for people who may benefit from targeted therapies or family risk information. **You may be eligible if...** - You are 18–39 years old at enrollment - You have been diagnosed with cancer at any age up to 39 years old (including pediatric cancers) - You are at any stage of diagnosis or treatment (newly diagnosed, in treatment, or a survivor) - You have an upcoming oncology appointment **You may NOT be eligible if...** - You are over 39 years old - You have already completed comprehensive hereditary cancer genetic testing - You are unable to use digital tools or communicate in English Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERTelemedicine

Undergo telehealth visit with genetic counselor for pretest genetic education

OTHERGenetic Testing

Complete standard of care genetic testing

OTHERTelemedicine

Undergo telehealth visit with genetic counselor for disclosure of results

OTHERInternet-Based Intervention

Receive access to Genetic Journey Chatbot

OTHEREducational Intervention

Complete digital pre-test genetic education

BEHAVIORALPatient Navigation

Utilize chatbot to answer questions, assess barriers, and provide reminders for next steps during the testing period

OTHERInterview

Complete interview

OTHERSurvey Administration

Ancillary studies