RecruitingEarly Phase 1NCT07093060

The Effect of Oral Oxytocin and Atosiban on Social Attention

The Influence and Regulatory Role of Exogenous and Endogenous Oxytocin on Social Attention in Humans


Sponsor

University of Electronic Science and Technology of China

Enrollment

250 participants

Start Date

Jun 9, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

The main aim of the present study is to investigate whether orally (lingual spray) administered oxytocin influences human social attention and behaviors via oxytocin receptors and whether its effects are dose- and task-dependent.


Eligibility

Sex: MALEMin Age: 18 YearsMax Age: 35 Years

Inclusion Criteria1

  • Healthy male subjects without past or current psychiatric or neurological disorders

Exclusion Criteria3

  • History of or current neurological/psychiatric disorders;
  • Use of psychotropic medications (including nicotine)
  • Visual impairments

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

DRUGOxytocin lower dose (24IU)

Oxytocin (24IU) will be administered as a lingual spray (6, 0.1 puffs (4IU per puff) of spray on and under the tongue)

DRUGOxytocin higher dose (48IU)

48IU oxytocin administered as a lingual spray (6, 0.1ml sprays (8IU per puff) on or under the tongue)

DRUGAtosiban

150ug atosiban administered by lingual sprays (6, 0.1ml sprays on and under the tongue)

DRUGPlacebo

Placebo administered as a lingual spray (6, 0.1 ml sprays one and under the tongue. Placebo has the same composition of 0.9% saline and glycerol as for oxytocin and atosiban interventions


Locations(1)

School of Life science and Technology, University of Electronic Science and Technology of China

Chengdu, Sichuan, China

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT07093060


Related Trials